Child-Pugh Score for Cirrhosis Mortality

Child-Pugh Score for Cirrhosis Mortality

Predicts severity and prognosis in chronic liver disease

Child-Pugh Score for Cirrhosis Mortality

Child-Pugh Score for Cirrhosis Mortality

Predicts severity and prognosis in chronic liver disease

Total Bilirubin (mg/dL)
Measure of liver function
Serum Albumin (g/dL)
Indicator of liver synthetic function
INR (International Normalized Ratio)
Measure of blood clotting
Ascites
Presence of fluid in the peritoneal cavity
Hepatic Encephalopathy
Brain dysfunction due to liver insufficiency
Child-Pugh Score 0 Class A (Well-compensated disease, 1-2 year survival ~95-100%)
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Instructions

The Child-Pugh Score is used to assess the severity of chronic liver disease and estimate prognosis in cirrhosis. To calculate the score, evaluate five clinical and laboratory parameters: total bilirubin, serum albumin, INR or prothrombin time, presence of ascites, and hepatic encephalopathy. Each parameter is assigned a score from 1 to 3 based on severity. Add the points to obtain the total score.

Overview
When to use
Why use
Evidences

Interpretation

Total Score

Class

5–6

A

7–9

B

10–15

C

The Child–Turcotte–Pugh (Child‑Pugh) score was introduced to stratify surgical risk in cirrhosis and later modified by Pugh et al. to replace “nutritional status” with prothrombin time; it sums five variables (bilirubin, albumin, INR/PT, ascites, encephalopathy) into classes A(5–6), B(7–9), C(10–15) for prognostic staging
https://pmc.ncbi.nlm.nih.gov/articles/PMC5218597/

 

StatPearls summarizes that higher Child‑Pugh classes correlate with worse hepatic function and mortality risk, guiding decisions on procedures, medications, and transplant referral
https://www.ncbi.nlm.nih.gov/books/NBK542308/

 

EASL guidance on decompensated cirrhosis uses Child‑Pugh to frame severity (e.g., Child‑Pugh C denotes advanced decompensation requiring intensive management and transplant evaluation) within broader care pathways for complications.
https://easl.eu/wp-content/uploads/2018/10/decompensated-cirrhosis-English-report.pdf 

Overview
When to use
Why use
Evidences

The Child-Pugh Score is a clinical tool designed to assess the severity of chronic liver disease, particularly cirrhosis. Developed in the 1960s and later modified, it remains a widely used system for estimating survival and determining treatment strategies. The score incorporates both biochemical values and clinical features, recognizing that cirrhosis impacts not only liver function but also systemic health.

The score is based on five parameters: serum bilirubin, serum albumin, prothrombin time (or INR), ascites, and hepatic encephalopathy. Each is assigned a score of 1 to 3 depending on severity, with higher numbers indicating worse function. The sum of these points categorizes patients into three classes: Child-Pugh A, B, or C. Class A represents well-compensated disease, Class B indicates significant functional compromise, and Class C denotes decompensated cirrhosis with poor prognosis.

Clinically, the Child-Pugh Score is valuable in multiple contexts. It helps estimate survival rates, inform timing of liver transplantation referral, and guide decisions on surgical or interventional procedures. For example, patients in Class A may tolerate surgery, while those in Class C have high perioperative risk. The score also provides useful prognostic information for counseling patients and families about expected outcomes.

Overview
When to use
Why use
Evidences

Interpretation

Total Score

Class

5–6

A

7–9

B

10–15

C

The Child–Turcotte–Pugh (Child‑Pugh) score was introduced to stratify surgical risk in cirrhosis and later modified by Pugh et al. to replace “nutritional status” with prothrombin time; it sums five variables (bilirubin, albumin, INR/PT, ascites, encephalopathy) into classes A(5–6), B(7–9), C(10–15) for prognostic staging
https://pmc.ncbi.nlm.nih.gov/articles/PMC5218597/

 

StatPearls summarizes that higher Child‑Pugh classes correlate with worse hepatic function and mortality risk, guiding decisions on procedures, medications, and transplant referral
https://www.ncbi.nlm.nih.gov/books/NBK542308/

 

EASL guidance on decompensated cirrhosis uses Child‑Pugh to frame severity (e.g., Child‑Pugh C denotes advanced decompensation requiring intensive management and transplant evaluation) within broader care pathways for complications.
https://easl.eu/wp-content/uploads/2018/10/decompensated-cirrhosis-English-report.pdf 

Frequently Asked Questions

Features and Services FAQs

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What factors are included in the Child-Pugh Score?+
Does it replace the MELD score?+
How often should the score be reassessed?+
Can the score predict variceal bleeding risk?+
Is Class C always an indication for transplantation?+
Can Child-Pugh be used in acute liver failure?+

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